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2006•Medical Journal of Chinese People's HealthRequires access

The clinical effect of bFGF on recurrent oral ulcer

Aimei Shi

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Abstract

Objective:To study the effect of basic fibroblast growth factor(bFGF) on recurrent oral ulcer(ROU).Methods:138 Patients with ROU(minor aphthous ulcer) were divided into two groups randomly.The treated group including 70 patients was treated with bFGF spray,which was sprayed locally on the ulcer surface;the control group including 68 patients was treated with chlohexidine solution with the consistency of 0.2%.Results: In three days,the effective ratio of the treated group is 90.00%,while that of the control group is 61.76%,there is a statistically significant difference between those two groups(P0.05);the average healing time of ulcer of the treated group is much shorter than that of the control group(P0.05).Conclusions: bFGF could treat ROU effectively.

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What this paper is about

Objective:To study the effect of basic fibroblast growth factor(bFGF) on recurrent oral ulcer(ROU).Methods:138 Patients with ROU(minor aphthous ulcer) were divided into two groups randomly.The treated group including 70 patients was treated with bFGF spray,which was sprayed locally on the ulcer surface;the control group including 68 patients was treated with chlohexidine solution with the consistency of 0.2%.Results: In three days,the effective ratio of the treated group is 90.00%,while that of the control group is 61.76%,there is a statistically significant difference between those two groups(P0.05);the average healing time of ulcer of the treated group is much shorter than that of the control group(P0.05).Conclusions: bFGF could treat ROU effectively.

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Available abstract

Objective:To study the effect of basic fibroblast growth factor(bFGF) on recurrent oral ulcer(ROU).Methods:138 Patients with ROU(minor aphthous ulcer) were divided into two groups randomly.The treated group including 70 patients was treated with bFGF spray,which was sprayed locally on the ulcer surface;the control group including 68 patients was treated with chlohexidine solution with the consistency of 0.2%.Results: In three days,the effective ratio of the treated group is 90.00%,while that of the control group is 61.76%,there is a statistically significant difference between those two groups(P0.05);the average healing time of ulcer of the treated group is much shorter than that of the control group(P0.05).Conclusions: bFGF could treat ROU effectively.

Key concepts: Basic fibroblast growth factor, Medicine, Internal medicine, Gastroenterology, Surgery, Growth factor, Receptor

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