Clinical investigation of Wenxinkeli in the treatment of coronary heart disease with ventricular premature beats

Objective To investigate the efficacy of Wenxinkeli for coronary heart disease with ventricular premature beats.Methods 130 patients with ventricular premature beats from coronary heart disease were randomized into two groups.One group(n=70) received Wenxinkeli(9g,po,tid) for 14 days.Another controlled group of patients(n=60) were treated with Metoprolol(12.5mg,po,bid) for 14 days.Clinical syndromes and ECG were monitored and compared.Results There was no significant difference in syndrome controlling(77.14% vs 78.33%) and ECG recovery(75.71% vs 73.33%) between two groups(P0.05).However,the blood pressure decreased significantly in the controll group while there was no change in Wenxinkeli group(P0.05).Conclusion Wenxinkeli was effective in controlling coronary heart disease with ventricular premature beats which had no side effect on blood pressure,it could be used in clinical practice widely.