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2006•Nervous Diseases and Mental HealthRequires access

A comparative study of aripiprazole and haloperidol in the treatment of patient with treatment-resistant schizophrenia

Ya Su

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Abstract

Objective To compare the efficacy and side effects of aripiprazole and haloperidol on patients with treatment-resistant schizophrenia. Methods 78 patients with the diagnosis of treatment- resistant schizophrenia were randomly assigned to aripiprazole or haloperidol treatment for 12 weeks. Efficacy and side effects were measured with PANSS and TESS. Results The overall therapeutic effect of aripiprazole(61.54%) was superior to that of haloperidol (43.59%).There were statistical differences in the PANSS total scores and N or G scale scores between the two groups (P0.01). Conclusions Aripiprazole is superior to haloperidol in the treatment-resistant schizophrenia, especially to negative symptoms.

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What this paper is about

Objective To compare the efficacy and side effects of aripiprazole and haloperidol on patients with treatment-resistant schizophrenia. Methods 78 patients with the diagnosis of treatment- resistant schizophrenia were randomly assigned to aripiprazole or haloperidol treatment for 12 weeks. Efficacy and side effects were measured with PANSS and TESS. Results The overall therapeutic effect of aripiprazole(61.54%) was superior to that of haloperidol (43.59%).There were statistical differences in the PANSS total scores and N or G scale scores between the two groups (P0.01). Conclusions Aripiprazole is superior to haloperidol in the treatment-resistant schizophrenia, especially to negative symptoms.

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Available abstract

Objective To compare the efficacy and side effects of aripiprazole and haloperidol on patients with treatment-resistant schizophrenia. Methods 78 patients with the diagnosis of treatment- resistant schizophrenia were randomly assigned to aripiprazole or haloperidol treatment for 12 weeks. Efficacy and side effects were measured with PANSS and TESS. Results The overall therapeutic effect of aripiprazole(61.54%) was superior to that of haloperidol (43.59%).There were statistical differences in the PANSS total scores and N or G scale scores between the two groups (P0.01). Conclusions Aripiprazole is superior to haloperidol in the treatment-resistant schizophrenia, especially to negative symptoms.

Key concepts: Aripiprazole, Haloperidol, Schizophrenia (object-oriented programming), Psychology, Medicine, Negative symptom, Psychiatry, Internal medicine

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A comparative study of aripiprazole and haloperidol in the treatment of patient with treatment-resistant schizophrenia — Research Paper | ScholarLens