Analysis on 235 ADR case reports in our hospital

Objective:To investigate the features and relevant factors of adverse drug reactions(ADRs) occurred in our hospital in order to improve the rational administration in clinic.Methods:A total of 235 ADR case reports collected from our hospital in 2009 were classified and analyzed in terms of ADR reporting source,gender and age distribution of patients,previous history of allergies,dosage forms of the drugs and routes of administration,categories of ADR-inducing drugs and distribution of ADR-inducing antibacterial drugs,the organs or systems involved in ADRs and clinical manifestations,severity classification of ADRs and recoveries,etc.Results:In the total 235 case reports,the percentage of children under 12 years old accounted for 31.49%,and 82.13% of ADRs were induced by intravenous drip.The incidence of ADR cases was mainly induced by the antimicrobial drugs,accounted for 72.34%,among which quinolones(35.88%) and cephalosporins(32.94%) were the main varieties.The main clinical manifestations of ADRs were lesions of skin and its appendix(41.18%),followed by systemic damage and damage of digestive system.There were 27 new and serious ADR reports.Conclusion:More attention should be paid to adverse drug reactions.Monitoring and reporting of ADRs should be strengthened.