Analysis on Bacterial Distribution and Drug Resistance of Blood Culture in Haikou

Objective To understand the distribution of pathogens in blood culture of Hainan Province in order to provide references for correct choice of antimicrobial drugs in clinic.Methods Blood cultured pathogens distributions in 2011 were analyzed.The drug resistance of 59 common gram-negative bacilli against 23 antimicrobial drugs and 16 gram-positive cocci against 15 antimicrobial drugs were both also analyzed.Results 104 strains of pathogens were isolated from 1560 blood culture specimens with a positive rate of 6.67%.Among them,28 strains were Escherichia coli(26.93%),13 were false Burkholderia bacteria(12.50%),10 were Staphylococcus aureus(9.63%),8 were Klebsiella pneumoniae(7.70%),6 were Pseudomonas aeruginosa(5.77%) and 6 were Staphylococcus epidermidis(5.77%).72 strains were gram-negative bacteria(69.23%),29 strains were gram-positive bacteria(27.88%) and 3 strains were fungi(2.89%).59 strains commonly seen gram-negative bacteria were all sensitive to imipenem,and had above 85% resistance to ampicillin.False Burkholderia bacteria were sensitive to ceftazidime.The detection rate of Escherichia coli and Klebsiella pneumoniae ESBLS were 39.29%(11/28) and 37.50%(3/8) respectively.6 strains of commonly seen gram-positive bacteria were sensitive to linezolid,Tigecycline and vancomycin.The detection rate of MRSA was 30.00%(3/10).Conclusion Blood culture can detect various types of bacteria,and bloodstream infection caused by the false Burkholderia bacteria is worthy of the attention of the clinician in Hainan province.