Detection of urogenital mycoplasma and analysis of results of drug sensitivity test.

Objective To understand the infection rates of Ureaplasma urealyticum(Uu) and Mycoplasma hominis(Mh) and analyze the status of drug resistance of mycoplasma in nongonococcal urethritis(NGU) patients Methods Uu and Mh were cultured and mycoplasma isolates were identified and drug sensitivity test was conducted with Uu and Mh test kit provided by Yeoman Biological Engineering Factory in Zhuhaihe. Results A total of 275 cases were tested positive for mycoplasma out of the 798 specimens with a positive rate of 34.5%,Being 19.3% in the males and 45.3% in the females,showing significant difference(P0.01).The resistance rate of Uu to josamycin,doxycycline,roxithromycin,clarithromycin and minocycline were low(1.8%～14.3%),while that of Mh to josamycin,doxycycline and minocycline were low(11.1%).The resistance of mixed infection with Uu and Mh were high.Josamycin was the most effective antibiotics for Un and Mh(82.2%). Conclusion Un and Mh be cultured and drug sensitivity test be carried out in order to guide clinical use of antibiotics and delay the development of drug resistance.