Analysis of blood culture specimens from 4001 tumor patients

Objective To understand the pathogen distribution,contamination status and drug resistance of blood culture specimens from tumor patients.Methods The blood culture positive specimens were identified by microbiology instrument,and the results were analyzed retrospectively by WHONET 5.4 software and the medical history review.Results Two hundred and fifty-one pathogenic strains were found from the 401 blood culture samples.Another 10 isolates were considered as contaminant strains,in which 8 strains were coagulase-negative staphylococci( CNS).Over the years,the positive rate of blood culture was between 4.84% ～ 8.35%,with the average positive rate of 6.27%.The 251 strains included 73 strains of Escherichia coli( 29.08%),35 strains of CNS( 13.94%),33 strains of Klebsiella pneumoniae( 13.15%).The positive strains were mainly distributed in the department of chemotherapy,mainly Gram-negative bacteria infection.Conclusion The bloodstream infection pathogens were widely distributed in tumor patients,with gram negative bacillus infection dominant.The drug resistance rate of Gram-positive bacteria were heavier.The contaminant bacteria of blood culture are mainly CNS.