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2002•Heilongjiang yiyao kexueRequires access

The therapeutic effects of fluconazole on fungal keratitis compared with ketoconazole

Huang Yuqin

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Abstract

Aim: To investigate the therapeutic effects of fluconazole on fungal keratitis by a case-control study of fluconazole and ketoconazole. Methods: 30 cases of fungal keratitis were divided into fluconazole group (16 cases) and ketoconazole group(14 cases) with corresponding drug used. Results: 15 cases healed after treatment with fluconazole and 8 cases healed with ketoconazole. The cure rates and the means of treatment duration are 93.8%, 17.5 days and 57.1%, 34.5 days respectively for fluconazole group and ketoconazole group. The differences in the cure rates and treatment duration between two groups are remarkable statistically (P0.05). Conclusion: Fluconazole is more effective than ketoconazole on treatment of fungal keratitis.

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What this paper is about

Aim: To investigate the therapeutic effects of fluconazole on fungal keratitis by a case-control study of fluconazole and ketoconazole. Methods: 30 cases of fungal keratitis were divided into fluconazole group (16 cases) and ketoconazole group(14 cases) with corresponding drug used. Results: 15 cases healed after treatment with fluconazole and 8 cases healed with ketoconazole. The cure rates and the means of treatment duration are 93.8%, 17.5 days and 57.1%, 34.5 days respectively for fluconazole group and ketoconazole group. The differences in the cure rates and treatment duration between two groups are remarkable statistically (P0.05). Conclusion: Fluconazole is more effective than ketoconazole on treatment of fungal keratitis.

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Available abstract

Aim: To investigate the therapeutic effects of fluconazole on fungal keratitis by a case-control study of fluconazole and ketoconazole. Methods: 30 cases of fungal keratitis were divided into fluconazole group (16 cases) and ketoconazole group(14 cases) with corresponding drug used. Results: 15 cases healed after treatment with fluconazole and 8 cases healed with ketoconazole. The cure rates and the means of treatment duration are 93.8%, 17.5 days and 57.1%, 34.5 days respectively for fluconazole group and ketoconazole group. The differences in the cure rates and treatment duration between two groups are remarkable statistically (P0.05). Conclusion: Fluconazole is more effective than ketoconazole on treatment of fungal keratitis.

Key concepts: Ketoconazole, Fluconazole, Fungal keratitis, Medicine, Keratitis, Antifungal, Therapeutic effect, Dermatology

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