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2009•Central South PharmacyRequires access

Optimization of ultrasound method to separate tanshinone IIA from Salvia

Yan Gu

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Abstract

Objective To optimize the extraction process of tanshinone ⅡA.Methods With tanshinone ⅡA for the detection index of evaluation,the extraction conditions were analyzed by orthogonal test.Results The optimum extraction of tanshinone ⅡA was as follows:ultrasound with 70% ethanol extraction 4 times,each time 30 min.Linearity for tanshinone ⅡA was good at 4.02~100.4 μg·mL-1.Conclusion Ultrasound extraction of tanshinone ⅡA is effective and quick,and it can be used for mass production.

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What this paper is about

Objective To optimize the extraction process of tanshinone ⅡA.Methods With tanshinone ⅡA for the detection index of evaluation,the extraction conditions were analyzed by orthogonal test.Results The optimum extraction of tanshinone ⅡA was as follows:ultrasound with 70% ethanol extraction 4 times,each time 30 min.Linearity for tanshinone ⅡA was good at 4.02~100.4 μg·mL-1.Conclusion Ultrasound extraction of tanshinone ⅡA is effective and quick,and it can be used for mass production.

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Available abstract

Objective To optimize the extraction process of tanshinone ⅡA.Methods With tanshinone ⅡA for the detection index of evaluation,the extraction conditions were analyzed by orthogonal test.Results The optimum extraction of tanshinone ⅡA was as follows:ultrasound with 70% ethanol extraction 4 times,each time 30 min.Linearity for tanshinone ⅡA was good at 4.02~100.4 μg·mL-1.Conclusion Ultrasound extraction of tanshinone ⅡA is effective and quick,and it can be used for mass production.

Key concepts: Extraction (chemistry), Chromatography, Ultrasound, Salvia miltiorrhiza, Chemistry, Medicine, Radiology, Alternative medicine

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