The Study on Clinical Significance in Treatment of Acute Myocardial Infarction by Early Intravenous Metoprolol and Investigating the Method to Use

Objective To investigate the clinical significance of acute myocardial infarction by early intravenous metoprolol,and to investigating the proper use.Methods 130 acute myocardial infarction patients were randomly divided into the metoprolol group and control group,each group of 65 cases,the control group were treated by the routine treatment,metoprolol group were treated oral metoprolol tablet,25mg/times,2 times/day,continuous treatment for 2 months.Results The ventricular arrhythmias,heart rate≤60 beats/min,cardiogenic shock,death,angina relieved of metoprolol group were better than the control group,P0.01;the average heart rate,CK-MB values,CK-MB peak time,duration of chest pain,ECG ST segment time,ST-segment elevation duration,EF values of metoprolol group and the control group were better than the control group,the difference was statistically significant,P0.01.Conclusion Early use of metoprolol were given in acute myocardial infarction patients have important clinical significance,can significantly reduce myocardial infarct size,correct cardiac remodeling,reduce ischemia caused by chest pain,reduce total mortality and sudden cardiac death,improve prognosis,have no significant adverse reactions,tolerance is good,worthy of clinical application,according to the patient's condition,the flexibility to use different dosing regimens.