Study on the Technique of Multi-slice Spiral CT Perfusion in the Application of Kidney Tumor

Objective To investigate the technique of Multi-slice Spiral CT perfusion with body tumor software package and evaluate the diagnosis value of its application of kidney tumor.Methods The multi-slice dynamic CT perfusion series was performed for thyroid perfusion with cine mode (1 s per rotation) on a multi-slice CT scanner (Siemens Somatom Sensation 40),40×0.6 mm collination,120 kV,60 mA Contrast injection was done by using 50 ml nonionic contrast agent (300 mgI/ml),at a flow rate of 4 ml/s with a power injector and 8 seconds delay ,and data acquisition lasted for 55 seconds. The parameters of CT perfusion such as blood flow(BF),mean transit time(MTT),and permeability surface(PS)were measured and statistically analyzed in patients with kidney carcinoma(n=16),and benign kidney disease(n=15) by pathology, respectively, on a siemens-mmwp workstation using Perfusion 2 software package (siemens)with deconvolution method.Results The images of perfusion with multi-slice CT could be readily obtained. Perfusion images can cleraly and directly display tumor diameter and outlines and quantitatively monitor blood perfusion status of tumor inner structures. The mean BF,BV,MTT and PS.The mean BF ,BV ,MTT and PS in kidney carcinoma were (250.81±21.88)ml/(100 g·min)、(19.01±4.10)ml/100 g、(9.87±3.90)s、(15.27±8.02)ml/(100 g·min),respectively .The mean BF,BV,MTT and PS in benign group were (70.82±6.91)ml/(100 g·min)、(8.19±2.40)ml/100 g、(10.11±1.67)s、(3.18±2.55)ml/(100 g·min),respectively.The mean BF、BV、PS between two groups had significant difference(P0.05).However,the mean MTT were not statistically significant(P0.05).Conclusion Perfusion MSCT is valuable for the differentiation of benign from malignant in kidney tumor.