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2009•Chinese Journal of General PracticeRequires access

The Influence of Acute Pancreatitis on Coagulation Function

Yang Gong-an

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Abstract

Objective To explore the changes of blood coagulation function and clinical significances in 56 cases of acute pancreatitis(AP).Methods Prothrombin time(PT),international normalized ratio(INR),activated partial thromboplastin time(APTT) and fibrinogen(FIB) concentration of 56 patients in AP group and normal control(NC) group were detected by full automatic blood coagulation analyzer.Results There was no statistical difference between mild AP(MAP) group and NC group(P0.05),but PT,APTT and FIB in severe AP(SAP) group were significiantly different compared with MAP group and NC group(P0.01).Conclusion PT,APTT and FIB of SAP patients prolong significantly,it shows a bad prognosis.

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What this paper is about

Objective To explore the changes of blood coagulation function and clinical significances in 56 cases of acute pancreatitis(AP).Methods Prothrombin time(PT),international normalized ratio(INR),activated partial thromboplastin time(APTT) and fibrinogen(FIB) concentration of 56 patients in AP group and normal control(NC) group were detected by full automatic blood coagulation analyzer.Results There was no statistical difference between mild AP(MAP) group and NC group(P0.05),but PT,APTT and FIB in severe AP(SAP) group were significiantly different compared with MAP group and NC group(P0.01).Conclusion PT,APTT and FIB of SAP patients prolong significantly,it shows a bad prognosis.

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Available abstract

Objective To explore the changes of blood coagulation function and clinical significances in 56 cases of acute pancreatitis(AP).Methods Prothrombin time(PT),international normalized ratio(INR),activated partial thromboplastin time(APTT) and fibrinogen(FIB) concentration of 56 patients in AP group and normal control(NC) group were detected by full automatic blood coagulation analyzer.Results There was no statistical difference between mild AP(MAP) group and NC group(P0.05),but PT,APTT and FIB in severe AP(SAP) group were significiantly different compared with MAP group and NC group(P0.01).Conclusion PT,APTT and FIB of SAP patients prolong significantly,it shows a bad prognosis.

Key concepts: Medicine, Partial thromboplastin time, Fibrinogen, Prothrombin time, Thrombin time, Coagulation, Acute pancreatitis, Internal medicine

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