2002Chinese Journal of Child Health CareRequires access

Changes of Peripheral Hemogram in Children of Slight and Moderate Iead Poisoning.

Dong Huang

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Abstract

To investigate the changes of peripheral hemogram in the children of slight and moderate lead poisoning. 3 170 children were divided into two groups based on blood lead level(BPb):normal group(BPb100μg/L)and lead poision group(BPb≥100μg/L).Peripheral hemogram,included hemoglobin(HGB),erythrocyte(RBC),hematocrit(HCT),mean corpuscular volume(MCV),mean corpuscular hemoglobin(MCH),mean corpuscular hemoglobin concentration(MCHC),leucocyte(WBC),platelet(PLT),mean platelet volume(MPV)and platelet distribution width(PDW)were measured in both groups. In poision group,WBC and PLT were significant lower( P 0.01),while MPV and PDW were significant higher( P 0.01) than normal group. There was no significant difference in HGB,RBC,HCT,MCV,MCH and MCHC( P 0.05) in both groups. [Conclusions] Slight and moderate lead poison could cause WBC and PLT level decreased in children, and HGB and RBC level were not obvious change.

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What this paper is about

To investigate the changes of peripheral hemogram in the children of slight and moderate lead poisoning. 3 170 children were divided into two groups based on blood lead level(BPb):normal group(BPb100μg/L)and lead poision group(BPb≥100μg/L).Peripheral hemogram,included hemoglobin(HGB),erythrocyte(RBC),hematocrit(HCT),mean corpuscular volume(MCV),mean corpuscular hemoglobin(MCH),mean corpuscular hemoglobin concentration(MCHC),leucocyte(WBC),platelet(PLT),mean platelet volume(MPV)and platelet distribution width(PDW)were measured in both groups. In poision group,WBC and PLT were significant lower( P 0.01),while MPV and PDW were significant higher( P 0.01) than normal group. There was no significant difference in HGB,RBC,HCT,MCV,MCH and MCHC( P 0.05) in both groups. [Conclusions] Slight and moderate lead poison could cause WBC and PLT level decreased in children, and HGB and RBC level were not obvious change.

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Available abstract

To investigate the changes of peripheral hemogram in the children of slight and moderate lead poisoning. 3 170 children were divided into two groups based on blood lead level(BPb):normal group(BPb100μg/L)and lead poision group(BPb≥100μg/L).Peripheral hemogram,included hemoglobin(HGB),erythrocyte(RBC),hematocrit(HCT),mean corpuscular volume(MCV),mean corpuscular hemoglobin(MCH),mean corpuscular hemoglobin concentration(MCHC),leucocyte(WBC),platelet(PLT),mean platelet volume(MPV)and platelet distribution width(PDW)were measured in both groups. In poision group,WBC and PLT were significant lower( P 0.01),while MPV and PDW were significant higher( P 0.01) than normal group. There was no significant difference in HGB,RBC,HCT,MCV,MCH and MCHC( P 0.05) in both groups. [Conclusions] Slight and moderate lead poison could cause WBC and PLT level decreased in children, and HGB and RBC level were not obvious change.

Key concepts: Mean corpuscular volume, Mean platelet volume, Mean corpuscular hemoglobin, Mean corpuscular hemoglobin concentration, Hematocrit, Hemoglobin, Platelet, Internal medicine

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