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2002•Carcinogenesis,Teratogenesis and MutagenesisRequires access

MUTAGENICITY OF ORGANIC EXTRACTS OF TAP WATER IN A CERTAIN CITY IN MICE

Jiang Cheng-mei

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Abstract

Purpose: To explore the mutagenicity of organic extracts of tap water in a certain city in mice. Methods: Each 200 L of water was collected separately from Huai river source water, water of clarifying filtration, chlorinated tap water and reservoir's water. After being adsorbed and concentrated, water samples were poured into mouse stomaches. Micronucleus frequency in mouse thoracic bone-marrow polychromatic erythrocyte (PCE) and sperm deformity rate were determined. Results: Mutagenicity of some degree were determined from Huai river source water and chlorinated tap water. The order of mutagenic intensity was as follows; chlorinated tap waterreservoir's watersource waterwater of clarifying filteration. Conclusions: The source water was contaminated by organic mutagens. After coagulation and precipitation, mutagenicity of source water decreased because some mutagenic organic chemicals could be removed. While chlorination increased mutagenicity of tap water.

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What this paper is about

Purpose: To explore the mutagenicity of organic extracts of tap water in a certain city in mice. Methods: Each 200 L of water was collected separately from Huai river source water, water of clarifying filtration, chlorinated tap water and reservoir's water. After being adsorbed and concentrated, water samples were poured into mouse stomaches. Micronucleus frequency in mouse thoracic bone-marrow polychromatic erythrocyte (PCE) and sperm deformity rate were determined. Results: Mutagenicity of some degree were determined from Huai river source water and chlorinated tap water. The order of mutagenic intensity was as follows; chlorinated tap waterreservoir's watersource waterwater of clarifying filteration. Conclusions: The source water was contaminated by organic mutagens. After coagulation and precipitation, mutagenicity of source water decreased because some mutagenic organic chemicals could be removed. While chlorination increased mutagenicity of tap water.

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Available abstract

Purpose: To explore the mutagenicity of organic extracts of tap water in a certain city in mice. Methods: Each 200 L of water was collected separately from Huai river source water, water of clarifying filtration, chlorinated tap water and reservoir's water. After being adsorbed and concentrated, water samples were poured into mouse stomaches. Micronucleus frequency in mouse thoracic bone-marrow polychromatic erythrocyte (PCE) and sperm deformity rate were determined. Results: Mutagenicity of some degree were determined from Huai river source water and chlorinated tap water. The order of mutagenic intensity was as follows; chlorinated tap waterreservoir's watersource waterwater of clarifying filteration. Conclusions: The source water was contaminated by organic mutagens. After coagulation and precipitation, mutagenicity of source water decreased because some mutagenic organic chemicals could be removed. While chlorination increased mutagenicity of tap water.

Key concepts: Tap water, Environmental chemistry, Water source, Chemistry, Contamination, Micronucleus test, Micronucleus, Pollutant

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