2005China Preventive MedicineRequires access

Study on Mutagenicity of Nonvolatile Organic Compounds of Drinking Water in N City

Jian Zheng

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Abstract

Objective To study the mutagenicity of the nonvolatile organic compounds(NOCs)in drinking water in N city. Methods XAD-2 resin were used to extract the organic matters in water.The Ames test,the micronucleus assay and the sperm morphologic test were used to analyze the mutagenicity of the nonvolatile organic compounds(NOCs)in water,for the main waterworks' source water,the clarified filtration water and the chlorinated tap water in N city. Results When the chlouinated tap water dosage was 50L/ml,micronucleus rate and seed deformity rate were significantly higher than that in normal group(P0.05).When the chlorinated tap water dosage were 5L/plate,TA 98-S9 MR=4.92,TA 98+S 9 MR=2.69. Conclusions The chlorinated tap water were showed Mutagenicity in some degree,but there were not mutagenicity found in the source water and the clarifying fillration water.Chlorination can enhance mutagenicity of tap water.

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Objective To study the mutagenicity of the nonvolatile organic compounds(NOCs)in drinking water in N city. Methods XAD-2 resin were used to extract the organic matters in water.The Ames test,the micronucleus assay and the sperm morphologic test were used to analyze the mutagenicity of the nonvolatile organic compounds(NOCs)in water,for the main waterworks' source water,the clarified filtration water and the chlorinated tap water in N city. Results When the chlouinated tap water dosage was 50L/ml,micronucleus rate and seed deformity rate were significantly higher than that in normal group(P0.05).When the chlorinated tap water dosage were 5L/plate,TA 98-S9 MR=4.92,TA 98+S 9 MR=2.69. Conclusions The chlorinated tap water were showed Mutagenicity in some degree,but there were not mutagenicity found in the source water and the clarifying fillration water.Chlorination can enhance mutagenicity of tap water.

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Available abstract

Objective To study the mutagenicity of the nonvolatile organic compounds(NOCs)in drinking water in N city. Methods XAD-2 resin were used to extract the organic matters in water.The Ames test,the micronucleus assay and the sperm morphologic test were used to analyze the mutagenicity of the nonvolatile organic compounds(NOCs)in water,for the main waterworks' source water,the clarified filtration water and the chlorinated tap water in N city. Results When the chlouinated tap water dosage was 50L/ml,micronucleus rate and seed deformity rate were significantly higher than that in normal group(P0.05).When the chlorinated tap water dosage were 5L/plate,TA 98-S9 MR=4.92,TA 98+S 9 MR=2.69. Conclusions The chlorinated tap water were showed Mutagenicity in some degree,but there were not mutagenicity found in the source water and the clarifying fillration water.Chlorination can enhance mutagenicity of tap water.

Key concepts: Tap water, Ames test, Micronucleus test, Environmental chemistry, Water source, Chemistry, Water treatment, Mutagen

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