Screening Analysis of Irregular Antibodies of 5014 Blood Donors in Hohhot Area

[Objective]To analyze the frequency and distribution of irregular antibodies in Hohhot area so as to ensure the safety of blood transfusion.[Methods]Blood donors of Hohhot area were randomly selected in 2008;antibody screening cells,polybrene test and anti-human globulin test were adopted for antibody screening.[Results]The irregular antibodies were found in 9 samples(0.18%).The frequency of irregular antibodies in female was higher than that in male(P0.01)and Rh antibodies such as anti-D,anti-E,and anti-Ec C(55.6%)were common.One sample of Le antibodies was failed to be found by polybrene test.[Conclusion]Because of irregular antibodies resulting in hemolytic transfusion reaction,the investigation of irregular antibodies is very important for ensuring blood transfusion.Antibody screening must be done for massive plasma transfusion of female donors,severe patients and infants to ensure safety.