2011•Zhongguo shiyan fangjixue zazhiRequires access
Determination of Soluble Arsenic in Niuhuang Jiedu Tablets and Its Disassembled Presciption by AFS
Zhen Zhan
Open publisher page 3 citations
Abstract
Objective:To explore whether the compatibility of Niuhuang Jiedu tablets could reduce the toxicity of realgar,and which may be the possible herbal medicines that could reduce toxicity in the Niuhuang Jiedu tablets prescription.Method:Different groups about Niuhuang Jiedu Tablets and its disassembled prescription were arranged,treated with artificial gastric juice or artificial intestine juice,and then atom fluorescence spectrophotometry(AFS) was used to detect the content of soluble arsenic in the different groups samples.Result:The content of soluble arsenic in the whole prescription was significant lower than that in the single realgar(P0.01).The content of soluble arsenic in the whole prescription except for Gancao,Huangqin and Dahuang was significant higher than that in the whole prescription(P0.01).Conclusions:The compatibility for Niuhuang Jiedu tablets could reduce the toxicity of realgar,and Gancao,Huangqin and Dahuang may be the possible herbal medicines that could reduce toxicity.