Clinical Study of Chinese Medicine on Proteinuria of Chronic Glomerulonephritis

Objective To observe the effect of chinese medicine on the levels of urinary albumin in Chronic GlomerulonePhritis. Methods Forty patients were blocking assigned randomly to two groups,thirty patients in the treatment group and ten in the control group. Chinese medicine was given additionally to patients in the treatment group after decocting,one dose per day( taken in two times). Control group took Losartan Potassium 50 mg,once daily. The treatment course for both groups was eight weeks. The 24 h urinary albumin,scores of TCM syndrome and contents of microalbumin,β2-MG in urine and Alb of all subjects were observed. Results Compared with before treatment the24 h urinary albumin was obviously reduced in the treatment group,showing significant difference( P 0. 01). The urinary 24 h albumin decreased in the control group,with statistical significance( P 0. 05). Statistical difference existed between the treatment group and the control group after treatment( P 0. 05). Scores of TCM syndromes in treatment group decreased significantly comparing to 0th( P 0.01),but control group rise. According to the criterion of Chinese medicine syndrome therapeutical effect,the effective rate in Chinese medicine group was 66.7%,Losartan Potassium group was 20%( P 0. 01). However,the effective rate to Western medicines standards was 60% in Chinese medicine group,40% in Losartan Potassium group( P 0. 05). Conclusion The Chinese medicine was better than western medicine to improve clinical syndrome,to reduce urine protein and to delay the progression of renal function.