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2013•Hainan Yixueyuan xuebaoRequires access

Effects of Simvastatin on transient ischemic attack and its influence on lipids

Yang En-fang

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Abstract

Objective: To analyze the effects of Simvastatin on transient ischemic attack.Methods: A total of 92 patients with TIA were randomly divided into two groups,group A(45 patients) were given enteric-coated aspirin tablets,group B(47 patients) were treated with simvastatin.Therapeutic effects of the both groups were observed.Results:89.36% patients of group A showed improvement,higher than the 73.33% of group B(P0.05).After treatment,TC,TG,LDL level of group B was lower than that in group A,but HDL level was higher(P both0.05).In group B,the rate of cerebral infarction,and TIA recurrence rate were 6.38% and 10.64%,respectively,both were lower 22.22% and 28.89% of group A(P0.05).Conclusion: Simvastatin shows great effects on transient ischemic attack,it can significantly decrease lipid levels to reduce cerebral infarction incidence and recurrence rate,which is good for patients' prognosis.

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What this paper is about

Objective: To analyze the effects of Simvastatin on transient ischemic attack.Methods: A total of 92 patients with TIA were randomly divided into two groups,group A(45 patients) were given enteric-coated aspirin tablets,group B(47 patients) were treated with simvastatin.Therapeutic effects of the both groups were observed.Results:89.36% patients of group A showed improvement,higher than the 73.33% of group B(P0.05).After treatment,TC,TG,LDL level of group B was lower than that in group A,but HDL level was higher(P both0.05).In group B,the rate of cerebral infarction,and TIA recurrence rate were 6.38% and 10.64%,respectively,both were lower 22.22% and 28.89% of group A(P0.05).Conclusion: Simvastatin shows great effects on transient ischemic attack,it can significantly decrease lipid levels to reduce cerebral infarction incidence and recurrence rate,which is good for patients' prognosis.

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Available abstract

Objective: To analyze the effects of Simvastatin on transient ischemic attack.Methods: A total of 92 patients with TIA were randomly divided into two groups,group A(45 patients) were given enteric-coated aspirin tablets,group B(47 patients) were treated with simvastatin.Therapeutic effects of the both groups were observed.Results:89.36% patients of group A showed improvement,higher than the 73.33% of group B(P0.05).After treatment,TC,TG,LDL level of group B was lower than that in group A,but HDL level was higher(P both0.05).In group B,the rate of cerebral infarction,and TIA recurrence rate were 6.38% and 10.64%,respectively,both were lower 22.22% and 28.89% of group A(P0.05).Conclusion: Simvastatin shows great effects on transient ischemic attack,it can significantly decrease lipid levels to reduce cerebral infarction incidence and recurrence rate,which is good for patients' prognosis.

Key concepts: Simvastatin, Medicine, Aspirin, Group B, Group A, Cerebral infarction, Internal medicine, Incidence (geometry)

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