Culture and drug-sensitivity test of mycoplasma from 387 patients with sexually transmitted disease

Objective To investigate the infection rate and the drug sensitivity of mycoplasma from patients with sexually transmitted disease (STD) in Chonqing. Methods Data from 387 STD patients positive for mycoplasma culture were analyzed retrospectively. Results Among the mycoplasma infected patients, those at the age from 20 to 40 years old were susceptible to mycoplasma infection. There was no significant difference between the male and the female. Ureaplasma urealyticum (UU) was the main pathogen of non gonococcal urethritis (NGU). Results of the drug sensitivity test of the 9 antibiotics showed that the sensitivity rate to josamycin, minocycline and doxycycline was 94.06%, 88.89%, and 86.82%, respectively. However, the resistance rate to clindamycin, azithromycin, and roxithromycin was higher. Conclusion It is important for doctors to use antibiotics for the treatment of UU and/or mycoplasma hominis (Mh) infection based on the results of drug sensitivity test. At present, josamycin, minocycline, and doxycycline may be used as the first antibiotics to treat mycoplasma infection in Chongqing.