Potentiometric titration determination of sodium chloride in clindamycin phosphate and sodium chloride injection

Aim Determination of sodium chloride in clindamycin phosphate and sodium chloride injection by potentiometric titration.Methods In the method,argent electrode a indicator electrode, 0.1 mol·L -1 silver nitrate as titrant ,determining at normal temperature. Results The calibrataion curve was linear in the range of 9～90 mg of diogenin with correlation coefficient of 0.999 9 ,the average recovery was 99.7%,the precision(RSD) was 0.08%. Conclusion This method is quick and accurate,noninterference, it may be adopted for quality control of clindamycin phosphate and sodium chloride injection.