2012China Modern DoctorRequires access

The clinical value analysis of cystatin C and high-sensitivity C-reactive protein co-detection in diagnosis of early renal damage of type 2 diabetes

LI Fen

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Abstract

Objective To investigate the clinical value of cystatin C and high-sensitivity C-reactive protein co-detection in diagnosis of early renal damage of type 2 diabetes,designed to provide further guidance on clinical basis.Methods 62 patients with type 2 diabetes(T2DM) in our hospital from January 2009-January 2010 were selected as the subjects of observation,another 35 healthy volunteers were selected as the control group,using immunoturbidimetric assay for cystatin C and C-reactive protein levels,and application of statistical methods for statistical analysis.Results DM renal dysfunction group CysC,hs-CRP was significantly higher than the DM group with normal renal function and healthy control group,and the difference was statistically significant,P 0.05;CysC,hs-CRP joint detection was significantly higher than CysC,hs-CRP testing as a single indicator,the difference was statistically significant,P 0.05.Conclusion Cystatin C and high-sensitivity C-reactive protein co-detection in diagnosis of type 2 diabetes is better than individual indicator of early detection of renal damage,should be promoted and applied.

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Objective To investigate the clinical value of cystatin C and high-sensitivity C-reactive protein co-detection in diagnosis of early renal damage of type 2 diabetes,designed to provide further guidance on clinical basis.Methods 62 patients with type 2 diabetes(T2DM) in our hospital from January 2009-January 2010 were selected as the subjects of observation,another 35 healthy volunteers were selected as the control group,using immunoturbidimetric assay for cystatin C and C-reactive protein levels,and application of statistical methods for statistical analysis.Results DM renal dysfunction group CysC,hs-CRP was significantly higher than the DM group with normal renal function and healthy control group,and the difference was statistically significant,P 0.05;CysC,hs-CRP joint detection was significantly higher than CysC,hs-CRP testing as a single indicator,the difference was statistically significant,P 0.05.Conclusion Cystatin C and high-sensitivity C-reactive protein co-detection in diagnosis of type 2 diabetes is better than individual indicator of early detection of renal damage,should be promoted and applied.

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Available abstract

Objective To investigate the clinical value of cystatin C and high-sensitivity C-reactive protein co-detection in diagnosis of early renal damage of type 2 diabetes,designed to provide further guidance on clinical basis.Methods 62 patients with type 2 diabetes(T2DM) in our hospital from January 2009-January 2010 were selected as the subjects of observation,another 35 healthy volunteers were selected as the control group,using immunoturbidimetric assay for cystatin C and C-reactive protein levels,and application of statistical methods for statistical analysis.Results DM renal dysfunction group CysC,hs-CRP was significantly higher than the DM group with normal renal function and healthy control group,and the difference was statistically significant,P 0.05;CysC,hs-CRP joint detection was significantly higher than CysC,hs-CRP testing as a single indicator,the difference was statistically significant,P 0.05.Conclusion Cystatin C and high-sensitivity C-reactive protein co-detection in diagnosis of type 2 diabetes is better than individual indicator of early detection of renal damage,should be promoted and applied.

Key concepts: Cystatin C, Medicine, C-reactive protein, Renal function, Internal medicine, Type 2 diabetes, Gastroenterology, Diabetes mellitus

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