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2006•Chengde Yixueyuan xuebaoRequires access

EFFECT OF EMP ON THE EXPRESSION OF N-METHYL-D-ASPARTATE RECEPTOR PROTEIN IN HIPPOCAMPUS IN RATS

Yuhong Li

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Abstract

Objective:To explore the effect of EMP on the expression of N-methyl-D-aspartate receptor (NMDAR)protein in hippocampus in rats. Methods: Western blotting was applied to detect the expression of NMDAR protein in hippocampus before and after EMP exposure. Results: The NMDAR protein increased at 1h and reached the highest level at 24h after exposure (compared with control,P0.05),and decreased after that. Conclusions: There is a efficient compensatory mechanism by which new NMDAR protein can be synthesised to suit functions in central nervous system early after exposure.

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What this paper is about

Objective:To explore the effect of EMP on the expression of N-methyl-D-aspartate receptor (NMDAR)protein in hippocampus in rats. Methods: Western blotting was applied to detect the expression of NMDAR protein in hippocampus before and after EMP exposure. Results: The NMDAR protein increased at 1h and reached the highest level at 24h after exposure (compared with control,P0.05),and decreased after that. Conclusions: There is a efficient compensatory mechanism by which new NMDAR protein can be synthesised to suit functions in central nervous system early after exposure.

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Available abstract

Objective:To explore the effect of EMP on the expression of N-methyl-D-aspartate receptor (NMDAR)protein in hippocampus in rats. Methods: Western blotting was applied to detect the expression of NMDAR protein in hippocampus before and after EMP exposure. Results: The NMDAR protein increased at 1h and reached the highest level at 24h after exposure (compared with control,P0.05),and decreased after that. Conclusions: There is a efficient compensatory mechanism by which new NMDAR protein can be synthesised to suit functions in central nervous system early after exposure.

Key concepts: Hippocampus, NMDA receptor, Protein expression, Receptor, Blot, Internal medicine, Endocrinology, Central nervous system

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