Influences of Acupuncture Prescriptions on Serum GMP-140 and Their Clinical Effects in Stroke Patients

Objective To investigate the clinical therapeutic effects of three acupuncture prescriptions on stroke(cerebral infarction) and their influences on serum GMP-140 in the patients and sift out the optimal prescription.Methods Ninety cerebral infarction(acute stage) patients were recruited and randomly allocated to three groups: A(yang meridian points),B(yin meridian points) and C (combined yin and yang meridian points).After twenty-one days' treatment,the clinical therapeutic effects were evaluated and changes in serum GMP-140 examined in the three groups of patients,and the posttreatment outcomes were compared between the three group.Results Neural function was restored in all the three groups of cerebral infarction(acute stage) patients.The clinical efficacy rate was significantly higher in group C than in group A and B(P0.05).Serum GMP-140 was reduced to a significantly larger extent in group C than in group A and B(P0.05).Conclusion Acupuncture of combined yin and yang meridian points can heighten the clinical therapeutic effect on cerebral infarction(acute stage) and significantly decrease serum GMP-140 content,thereby reducing high platelet activity,improving the degree of platelet activation and the pathological blood viscosity and erythrocyte aggregation,ameliorating cerebral blood supply,preventing thrombus spreading and promoting the recovery of limb function.