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Detection of serum sICAM-1 in patients with malignant ovarian tumor and its clinical value

Huiling Pei

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Abstract

Objective To investigate soluble intercellular adhesion molecule-1(sICAM-1) and analyse its clinical value.Methods Double antibody sandwich ELISA method was applied to examine serum sICAM-1 in 54 patients with malignant ovarian tumor while the relationship between sICAM-1 and the clinical stages was studied.Results The concentrations of serum sICAM-1 in 54 cases with malignant ovarian tumors were higher obviously than the control group(P0.01),the serum sICAM- 1 with malignant ovavian tumors at late stages(Ⅲ～Ⅳ) was higher obviously than that at early stages (Ⅰ～Ⅱ)(P0.05).Conclusion Serum sICAM-1 may be used as a marker for monitoring the prog- nosis of ovarian carcinomae.

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What this paper is about

Objective To investigate soluble intercellular adhesion molecule-1(sICAM-1) and analyse its clinical value.Methods Double antibody sandwich ELISA method was applied to examine serum sICAM-1 in 54 patients with malignant ovarian tumor while the relationship between sICAM-1 and the clinical stages was studied.Results The concentrations of serum sICAM-1 in 54 cases with malignant ovarian tumors were higher obviously than the control group(P0.01),the serum sICAM- 1 with malignant ovavian tumors at late stages(Ⅲ～Ⅳ) was higher obviously than that at early stages (Ⅰ～Ⅱ)(P0.05).Conclusion Serum sICAM-1 may be used as a marker for monitoring the prog- nosis of ovarian carcinomae.

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Available abstract

Objective To investigate soluble intercellular adhesion molecule-1(sICAM-1) and analyse its clinical value.Methods Double antibody sandwich ELISA method was applied to examine serum sICAM-1 in 54 patients with malignant ovarian tumor while the relationship between sICAM-1 and the clinical stages was studied.Results The concentrations of serum sICAM-1 in 54 cases with malignant ovarian tumors were higher obviously than the control group(P0.01),the serum sICAM- 1 with malignant ovavian tumors at late stages(Ⅲ～Ⅳ) was higher obviously than that at early stages (Ⅰ～Ⅱ)(P0.05).Conclusion Serum sICAM-1 may be used as a marker for monitoring the prog- nosis of ovarian carcinomae.

Key concepts: Ovarian cancer, Medicine, Ovarian tumor, Internal medicine, Serum concentration, Antibody, Gastroenterology, Pathology

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Detection of serum sICAM-1 in patients with malignant ovarian tumor and its clinical value — Research Paper | ScholarLens