The clinical efficacy and safety of aripiprazole in the treatment of tic disorder

Objective To explore the effect and security of aripiprazole in the treatment of tic disorder. Methods 87 cases of children with tic disorder,who were in our hospital during from May 2010 to May 2013,were selected as clinical object of study.They were randomly divided into treatment group(45cases) and control group(42cases).The control group was treated with haloperidol,and the treatment group was treated by aripiprazole. Results The total efficacious rate of treatment group was significantly higher than that of the control group(P 0.05).After treatment 2 weeks,4 weeks,and 8 weeks,YGTSS scores of two groups were comparative differences(P0.01).The adverse reaction of the treatment group wassignificantly lower than that of the control group(P 0.05). Conclusion Aripiprazole can reduce children's tic score and the rate of adverse reactions for children with tic disorder. It is effective and safe,can be used as the effective way for the therapy of children with tic disorder.