2008Huazhong yixue zazhiRequires access

The clinical analysis of the 29 infantnewborn enterobacter cloacae septicaemia.

Sun XiaoHong

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Abstract

Objective To investigate the clinical characteristics of the infantnewborn enterobacter cloacae septicaemia and the characteristics of its drug sensitivity to find out the basis for the early diagnose and treatment.Methods Through history analysis of the clinical data and the results of the drug sensitivity of 29 infantnewborn diagnosed as enterobacter cloacae septicaemia from May 2005 to August 2007 in our hospital.Results Enterobacter cloacae septicaemia can cause the damage to the function of visceras,and the sensitivity of enterobacter cloacae to imipenem、amikacinand ciprofloxacin is up to 100%;All the Enterobacter cloacae were severely resistant to majority of cephalosporins Ⅲ,and 82.8% of them were susceptible to cephalosporins Ⅳ,32.4% of them were ESBLs which can produce Enterobacter cloacae.Conclusion Enterobacter cloacae septicaemia cases have the tendancy to increase,most of which are infected in the hospital and not sensitive to the common antibiotics.The carbapenem antibiotics like imipenem and cefepime are suggested to be the first option for the enterobacter cloacae infection.Enterobacter cloacae septicaemia can be treated with satisfactory effectiveness by prompt using sensitive antibiotics.

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Objective To investigate the clinical characteristics of the infantnewborn enterobacter cloacae septicaemia and the characteristics of its drug sensitivity to find out the basis for the early diagnose and treatment.Methods Through history analysis of the clinical data and the results of the drug sensitivity of 29 infantnewborn diagnosed as enterobacter cloacae septicaemia from May 2005 to August 2007 in our hospital.Results Enterobacter cloacae septicaemia can cause the damage to the function of visceras,and the sensitivity of enterobacter cloacae to imipenem、amikacinand ciprofloxacin is up to 100%;All the Enterobacter cloacae were severely resistant to majority of cephalosporins Ⅲ,and 82.8% of them were susceptible to cephalosporins Ⅳ,32.4% of them were ESBLs which can produce Enterobacter cloacae.Conclusion Enterobacter cloacae septicaemia cases have the tendancy to increase,most of which are infected in the hospital and not sensitive to the common antibiotics.The carbapenem antibiotics like imipenem and cefepime are suggested to be the first option for the enterobacter cloacae infection.Enterobacter cloacae septicaemia can be treated with satisfactory effectiveness by prompt using sensitive antibiotics.

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Available abstract

Objective To investigate the clinical characteristics of the infantnewborn enterobacter cloacae septicaemia and the characteristics of its drug sensitivity to find out the basis for the early diagnose and treatment.Methods Through history analysis of the clinical data and the results of the drug sensitivity of 29 infantnewborn diagnosed as enterobacter cloacae septicaemia from May 2005 to August 2007 in our hospital.Results Enterobacter cloacae septicaemia can cause the damage to the function of visceras,and the sensitivity of enterobacter cloacae to imipenem、amikacinand ciprofloxacin is up to 100%;All the Enterobacter cloacae were severely resistant to majority of cephalosporins Ⅲ,and 82.8% of them were susceptible to cephalosporins Ⅳ,32.4% of them were ESBLs which can produce Enterobacter cloacae.Conclusion Enterobacter cloacae septicaemia cases have the tendancy to increase,most of which are infected in the hospital and not sensitive to the common antibiotics.The carbapenem antibiotics like imipenem and cefepime are suggested to be the first option for the enterobacter cloacae infection.Enterobacter cloacae septicaemia can be treated with satisfactory effectiveness by prompt using sensitive antibiotics.

Key concepts: Enterobacter cloacae, Imipenem, Cefepime, Enterobacter, Cephalosporin, Microbiology, Antibiotics, Ciprofloxacin

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