The Synthesis of Tetra-(p-Nitrophenyl)Porphyrin under Microwave Irradiation

Tetra-(p-nitrophenyl)porphyrin was efficiently synthesized from pyrrole and p-nitrobenzaldehyde under microwave irradiation with lactic acid as catalyst for the first time.The effects of solvent,catalyst,microwave irradiation time,microwave irradiation power on the yield of tetra-(p-nitrophenyl)porphyrin were investigated.The results showed that the optimum reaction conditions are as follows:2.0 mL lactic acid as the catalyst in 30 mL nitrobenzene,p-nitrobenzaldehyde 0.01 mol,pyrrole 0.01 mol,microwave irradiation power 280 W,microwave irradiation time 16 min,the yield was up to 23.9%.