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Pulmonary Sclerosing Hemangioma:A Clinicopathologic Analysis of 32 Cases

Qiang Liu

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Abstract

Objective:To investigate the clinicopathological characteristics of pulmonary sclerosing hemangioma(PSH). Methods:Thirty-two cases of PSH were studied by HE staining,immunohistochemical staining,light microscopy and clinical data. Results:Of the 32 cases of PSH,3 cases were males and 29 cases were females.The average age was 51 years old(ranged from 31 to 62 years).13 cases were located in the left lung and 19 cases in the right lung.Pathological morphologic findings were solid,papillary, hemangiomatous,sclerotic pattern.Major structures of tumor cells were round and cuboidal.Cytoplasma was pale or red.Immunohistochemistry results showed that both round and cuboidal cells expressed TTF- 1,EMA,cuboidal cells also expressed PCK,round cells expressed Vimentin,Syn,CgA,NSE.Ki-671%.Follow-up information was available in all cases,no recurrences and metastasis was found.Conclusion:PSH is a rare and epithelial lung tumor.It usually occurs in middle-aged women and have a good prognosis.

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Objective:To investigate the clinicopathological characteristics of pulmonary sclerosing hemangioma(PSH). Methods:Thirty-two cases of PSH were studied by HE staining,immunohistochemical staining,light microscopy and clinical data. Results:Of the 32 cases of PSH,3 cases were males and 29 cases were females.The average age was 51 years old(ranged from 31 to 62 years).13 cases were located in the left lung and 19 cases in the right lung.Pathological morphologic findings were solid,papillary, hemangiomatous,sclerotic pattern.Major structures of tumor cells were round and cuboidal.Cytoplasma was pale or red.Immunohistochemistry results showed that both round and cuboidal cells expressed TTF- 1,EMA,cuboidal cells also expressed PCK,round cells expressed Vimentin,Syn,CgA,NSE.Ki-671%.Follow-up information was available in all cases,no recurrences and metastasis was found.Conclusion:PSH is a rare and epithelial lung tumor.It usually occurs in middle-aged women and have a good prognosis.

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Available abstract

Objective:To investigate the clinicopathological characteristics of pulmonary sclerosing hemangioma(PSH). Methods:Thirty-two cases of PSH were studied by HE staining,immunohistochemical staining,light microscopy and clinical data. Results:Of the 32 cases of PSH,3 cases were males and 29 cases were females.The average age was 51 years old(ranged from 31 to 62 years).13 cases were located in the left lung and 19 cases in the right lung.Pathological morphologic findings were solid,papillary, hemangiomatous,sclerotic pattern.Major structures of tumor cells were round and cuboidal.Cytoplasma was pale or red.Immunohistochemistry results showed that both round and cuboidal cells expressed TTF- 1,EMA,cuboidal cells also expressed PCK,round cells expressed Vimentin,Syn,CgA,NSE.Ki-671%.Follow-up information was available in all cases,no recurrences and metastasis was found.Conclusion:PSH is a rare and epithelial lung tumor.It usually occurs in middle-aged women and have a good prognosis.

Key concepts: Cuboidal Cell, Immunohistochemistry, Pathology, Medicine, Staining, Lung, Vimentin, Pathological

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