2009•Journal of clinical and experimental medicineRequires access
The efficacy of Xize Tang in treatment of patients with chronic hepatitis B
Zhimin Tang
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Abstract
Objective To observe the efficacy of Xize Tang in treatment of patients with chronic hepatitis B of damp-heat type(with resistant signs and symptoms)and to explore the effective treatment for chronic hepatitis B.Methods Eighty cases of chronic hepatitis B with damp-heat type were randomly divided into control group(40 patients)and treatment group(40 patients).Patients in control group were treated on the basis of conventional therapy for liver disease by oral administration of Ganlixin(glycyrrhizin),each 150mg,3 times per day,for a treatment course of 3 months for two courses.Patients in treatment group were treated on the basis of routine treatment for liver disease in addition with using Xize Tang(decoction)once a day,3 months as a course of treatment for two courses.Results The improvement of symptoms and restoring liver functions in patients of treatment group were superior to those of control group(P0.001,P0.01,P0.05),but the ALT normalization rate in patients of these two group was approximately similar.The HBV DNA negative inversion rate in patients of treatment group after treatment of 6 months was 7.5%,and it was 0 in patients of control group,HbeAg negative inversion rate and HBeAg seroconversion rates in treatment group and control group were 11.54%,11.54% and 4%,0 respectively.Conclusion Xize Tang has certain effect in treatment of patients with chronic hepatitis B of damp-heat type,so it is a better treatment option for patients who do not fit or agree with anti-virus therapy.