MRI Diagnosis of Dysgenesis of the Corpus Callosum Incorporate Encephalic Malformation

Objective To explore the MRI diagnostic value in dysgenesis of the corpus callosum incorporate encephalic malformation. Materials and Methods The MR findings of 18 cases with dysgenesis of the corpus callosum incorporate encephalic malformation were retrospectively analyzed. Results The complete lack of the corpus callosum was found in 10 cases, partial lack of the corpus callosum in 6 cases and thinning of the corpus callosum in 2 cases. The MRI findings of dysgenesis of the corpus callosum included enlargment of interhemispheric fissure with approaching to the anterior part of the third ventricle(100%); flat straightness and separated frontal horns; separated interventricular foramina; nearly parallel body part of lateral ventricles or decreased angle between the choroids plexus of the ventricle; dilatation and elevation of the third ventricle; enlarged occipital horns. Accompanying congenital anomalies of the central nervous system were gray matter heterotopia(3 cases), abnormalities of schizencephaly(2 cases), arachnoid cyst(3 cases), lipoma(4 cases), lack of septum pellucidum (1 case), smoothing cerebral gyri (1 case), porencephaly(3 cases), thalamic fusion(1 case), hollow cerebral gyri (1 case). Conclusion MRI can directly observe the morphologic construction of corpus callosum, MRI is the best method to diagnose the dysgenesis of the corpus callosum incorporate encephalic malformation.