Magnetic Resonance Imaging Analysis of Children's Corpus Callosum Dysplasia and Clinical Value

Objective To explore the magnetic resonance(MR) imaging features of corpus callosum dysplasia and the clinical application value. Methods Retrospective analysis MR imaging and clinical data of 132 children with corpus callosum dysplasia cases. Results Among 40 cases Simple corpus callosum dysplasia, 2 cases were corpus callosum completely not developed. partial not developed were 13 cases. 11 cases were total corpus callosum dysplasia. 14 cases were partial corpus callosum dysplasia. Simple corpus callosum dysplasia showed the tissue is partial or complete agenesis, partially or totally thinning. 92 cases were corpus callosum dysplasia with other brain development abnormal. In addition to simple the structure or morphological abnormalities of the corpus callosum, the enlargement of lateral ventricle, hydrocephalus, or transparent septum absence, cavum septi pellucidum, cerebral white matter dysplasia, gray matter heterotopia, split brain malformation, gyrus malformations, skull malformations, congenital epidermoid cyst and brain tumors, etc. Clinically, some children had no obvious symptoms and signs. Severe patients mainly showed varying degrees of retardation, epilepsy. clinical symptoms of simple corpus callosum dysplasia were milder than those with other abnormal brain development. Conclusion MRI can well display and assess the corpus callosum dysplasia, and the accompanied other abnormal brain development.