Changes of measured value of intraocular pressure after laser in situ keratomileusis and its correlation with central corneal thickness

Objective To investigate the relation of the measured value of intraocular pressure(IOP)after laser in situ keratomileusis (LASIK) and central corneal thickness (CCT) and its significance. Methods Fifty patients (100eyes) with high myopia were performed LASIK. Before and 3months after operation ,IOP was measured by NIDEK NT-2000 tonometry individually,CCT was measured by ultrasound corneal pachymeter ,and the correlation between the two indexes was analyzed. Results The IOP before and after operation were (13.99±2.37),(11.89±2.73)mmHg,P0.01.The CCT were (529.63±27.82),(452.39±36.11)μm,P0.01. The CCT was positively associated with IOP before or after operation (r=0.46,P=0.01.r=0.43,P=0.02). The changing magnitude of IOP and CCT were(-2.68±1.78)mmHg and (77.45± 19.88)μm,which were negatively correlated with each other(r=-0.523,P0.01).Conclusions The measured value of IOP after LASIK decrease with the reduction of CCT,which does not represent the change of IOP intrinsically. Patients with questionable intraocular hypotension signs after LASIK should be given necessary examination.