An Investigation on the Important Parameters that Affect Intraocular Pressure after Laser in Situ Keratomileusis for Myopia

Purpose To explore the changes in intraocular pressure(IOP)and affecting parameters after laser in situ keratomileusis(LASIK)for myopia.Methods In this prospective study,760 eyes of 393 patients who underwent LASIK were included.Spherical equivalent dioptre(D),preoperative central corneal thickness(CCT),preoperative IOP,preoperative corneal curvature(K),ablation depth(T),change of corneal curvature(AK),patient age and sex were analyzed to determine the contribution and correlation to the underestimation of IOP(AP).Results D(r =0.380,P = 0.000),preoperative CCT(r = 0.224,P = 0.000),preoperative IOP(r = 0.657,P = 0.000),K(r = 0.126,P= 0.001),T(r =0.389,P =0.000),AK(r =0.363,P =0.000)were statistically significant for Ap.The preoperative IOP level is the most important parameter that affect AP.The regression equation obtained was AP =-7.722+0.029 T+ 0.582 IOP-0.005 CCT+0.116 K.Conclusion The preoperative IOP level is the most important parameter that affect the underestimation of IOP after LASIK for myopia.The higher the preoperative IOP is,the higher the underestimation of IOP is.(Chin J Ophthalmol and Otorhiuolaryngo1,2007,7:220-221)