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Studies on chemical constituents of the roots of Scutellaria viscidula Bge.

Suixu Xu

Open publisher page 9 citations

Abstract

Objective To study the chemical constituents of the roots of Scutellaria viscidula.Methods Various chromatographic techniques were used to separate and purify its constituents.The structures were determined by chemical evidence and spectral analyses.Result Eight compounds were isolated and their structures were identified as oroxylin A (Ⅰ), wogonin (Ⅱ), chrysin (Ⅲ), 5,7,4′-trihydroxy-8-methoxyflavone (Ⅳ), baicalein (Ⅴ),viscidulin Ⅲ(Ⅵ), viscidulin Ⅰ(Ⅶ), and wogonoside (Ⅷ).Conclusion Compound Ⅲ and Ⅳ are isolated from Scutellaria viscidula Bge. for the first time.

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What this paper is about

Objective To study the chemical constituents of the roots of Scutellaria viscidula.Methods Various chromatographic techniques were used to separate and purify its constituents.The structures were determined by chemical evidence and spectral analyses.Result Eight compounds were isolated and their structures were identified as oroxylin A (Ⅰ), wogonin (Ⅱ), chrysin (Ⅲ), 5,7,4′-trihydroxy-8-methoxyflavone (Ⅳ), baicalein (Ⅴ),viscidulin Ⅲ(Ⅵ), viscidulin Ⅰ(Ⅶ), and wogonoside (Ⅷ).Conclusion Compound Ⅲ and Ⅳ are isolated from Scutellaria viscidula Bge. for the first time.

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Available abstract

Objective To study the chemical constituents of the roots of Scutellaria viscidula.Methods Various chromatographic techniques were used to separate and purify its constituents.The structures were determined by chemical evidence and spectral analyses.Result Eight compounds were isolated and their structures were identified as oroxylin A (Ⅰ), wogonin (Ⅱ), chrysin (Ⅲ), 5,7,4′-trihydroxy-8-methoxyflavone (Ⅳ), baicalein (Ⅴ),viscidulin Ⅲ(Ⅵ), viscidulin Ⅰ(Ⅶ), and wogonoside (Ⅷ).Conclusion Compound Ⅲ and Ⅳ are isolated from Scutellaria viscidula Bge. for the first time.

Key concepts: Wogonin, Baicalein, Scutellaria, Chrysin, Chemistry, Baicalin, Chemical constituents, Chromatography

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