2005•Unpublished venueRequires access

Advancement of Heparanase in Gastrointestinal Tumor

Ji W

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Abstract

Objective: To sum up the structure and the function of heparanase, and correlations with gastrointestinal tumorigenesis and metastasis and their possible mechanism. Methods: Consulting related literatures home and abroad. Results and conclusion: Heparanase is the key enzyme to degrade extracellular matrix and closely related to tumor cell invasion and metastasis,become a novel cancer therapy target in gastrointestinal tumor.

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What this paper is about

Objective: To sum up the structure and the function of heparanase, and correlations with gastrointestinal tumorigenesis and metastasis and their possible mechanism. Methods: Consulting related literatures home and abroad. Results and conclusion: Heparanase is the key enzyme to degrade extracellular matrix and closely related to tumor cell invasion and metastasis,become a novel cancer therapy target in gastrointestinal tumor.

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Available abstract

Objective: To sum up the structure and the function of heparanase, and correlations with gastrointestinal tumorigenesis and metastasis and their possible mechanism. Methods: Consulting related literatures home and abroad. Results and conclusion: Heparanase is the key enzyme to degrade extracellular matrix and closely related to tumor cell invasion and metastasis,become a novel cancer therapy target in gastrointestinal tumor.

Key concepts: Heparanase, Medicine, Metastasis, Extracellular matrix, Carcinogenesis, Cancer, Mechanism (biology), Cancer research

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