A Clinical Study on the Effect of Droperidol on Preventing Postoperative Nausea and Vomiting after Laparoscopic Cholecystectomy

Objective To observe the efficacy of droperidol i n preventing postoperative nausea and vomiting after laparoscopic cholecystectomy. Methods Fifty patients undergoing laparoscopic cholecystectomy were randomly divided into two groups:droperidol group D(n=25)and control group C(n=25).The patients in group D were intravescularly administered with 1.25 mg droperidol 5 minutes before anesthesia was induced, while the patients in gro up C were not.Nausea,vomiting,sedation of patiens were observed in the following 24 hours.Results The incidence of postoperative nausea and vomitin g was 16% in group D,72% in group C.There was a great significance between them and was no significant difference of sedation score between group D and C. Conclusion Preventive administration of droperidol can effictively preven t postoperative nausea and vomiting.