2008•China Medical HeraldRequires access

Prophylactic effects of small-dose Doperidol on nausea and vomiting after la-paroscopic cholecystectomy

Yongmei Xu

Abstract

Objective:To investigate the preventive effect of small-dose Droperidol against postoperative nausea and vomit-ing(PONV) after laparoscopic cholecystetomy.Methods:Ninety ASA I or II patients were randomly divided into On-dansetron(4 mg,IV) group and Droperidol(10 μg/kg,IV) group,with 45 patients in each group.Nausea and vomiting were observed during 24 hours of post operation.Results:No significant differences were observed in the terms of incidence rate of postoperative nausea between Ondansetron group(26.7 %)and Droperidol group(31.1%),and so did postoperative nausea incidences(20.0%,15.6%)(P0.05).No remarked adverse effects were observed within 24 hours of postoperatively.Conclu-sion:Intravenous Ondansetron(4 mg) or Droperidol(10 μg/kg) can prevent PONV with similar efficacy and safety.

About this research paper

What this paper is about

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Droperidol, Medicine, Nausea, Ondansetron, Vomiting, Anesthesia, Postoperative nausea and vomiting, Adverse effect