Clinical value of continuous high-level positive end-expiratory pressure in treating pulmonary endogenous acute respiratory distress syndrome

Objective:To explore the clinical value of continuous high-level positive end-expiratory pressure(PEEP)in treating pulmonary endogenous acute respiratory distress syndrome(ARDS)in order to provide basis for mechanical ventilation treatment of ARDS.Methods:Clinical data of 70cases of pulmonary endogenous ARDS treated in my hospital were analyzed.Patients were divided into the observation group and the control group based on whether their PEEP12cmH2O.The improvement of PaO2and PaCO2,barotrauma incidence,duration in ICU,duration of mechanical ventilation and mortality rate of patients in both groups were compared.Results:0h,24hand72hafter mechanical ventilation,there were no difference in the improvement of PaO2and PaCO2(P0.05);but after 1week's mechanical ventilation,PaO2and PaCO2in the observation group and the control group were(159.41±29.16),(44.51±10.23)and(286.14±38.46),(40.21±8.97)respectively,which were of significant differences(P0.05).The duration in ICU,duration of mechanical ventilation and mortality rate of patients in the observation group were(11.78±9.86),(7.56±6.09),34.51%respectively,while(6.51±8.97),(3.98±5.76),18.76%respectively in the control group.There were significant differences between both groups(P0.05).There were 3barotrauma in the observation group,but no barotrauma occurred in the control group.Conclusion:Continuous high-level PEEP in treating pulmonary endogenous ARDS patients can not improve the oxygenation of the patients effectively,and it may prolong the patients' duration in ICU and increase the mortality rate of the patients.