2007•Zhongguo shiyan fangjixue zazhiRequires access

Protective Effects of Compound Huanggen on Immunological Liver lnjury

Wang Qin

Abstract

Objective:To investigate the protective effect of Compound Huanggen on immunological liver injury in mice.Method:The model of hepatic damage was induced by BCG+LPS.The ALT and AST level in serum and MDA,SOD,GSH-PX activites in liver homogenate were assayed and dimensions of hepatic damage in the histopathology were observed.Results:Compound Huanggen was found to significantly decrease the serum transaminase activities,Meanwhile decreased MDA content and inhilited SOD,GSH-PX activities in liver homogenate.Conclusion:Compound Huanggen show significant protective action on immunological liver injury in mice.

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Key concepts: Histopathology, Liver injury, Glutathione, Pharmacology, Chemistry, Transaminase, Immunology, Internal medicine