Study on Effect of Fufangchongcaolingzhi Preparation on Alleviating Physical Fatigue

[Objective] To study the effect of Fufangchongcaolingzhi Preparation on alleviating physical fatigue.[Methods]Divide the ICR mouse into four groups,including low dose group(0.166 g/kg),medium dose group(0.333 g/kg),high dose group(1.000 g/kg)and control group,according to the weight,with 10 mice of one group.Feed the mice with test sample by gavage once a day for 30 days.Then,conduct the following experiments,swimming under burden,serum urea assay,hepatic glycogen assay,and serum lactic acid assay,respectively.[Results]The swimming time under burden of medium dose,high dose and control group mice were 850±80,771±125 and 657±116(sec),which of the medium dose group and high dose group significantly longer than the control one(P0.05).The contents of hepatic glycogen of low dose,medium dose,high dose and control group were 1347±50,1852±134,1638±580 and 1275±306(mg/100g).The medium dose group was significantly higher than the control one(P0.05).The area under curve(AUC)of lactic acid in the serum of low dose,medium dose,high dose and control group were 89.49±18.86,95.26±17.64,83.04±17.12 and 123.03±19.31(mmol/L).The AUC of lactic acid in all test groups were much lower than in control group(P0.05).The level of serum urea in all test groups were similar to the control group(P0.05).These results indicated that the Fufangchongcaolingzhi Preparation can prolong the swimming time of mouse under burden,increase the content of mouse hepatic glycogen,and reduce the AUC of mouse serum lactic acid.[Conclusion]Fufangchongcaolingzhi Preparation as a health food can make beneficial effect by relieving the physical fatigue.