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Different blood purification of parathyroid hormone in uremic patients and β_2-microglobulin removal efficiency comparison

Rong Ren

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Abstract

【Objective】 To observe the scavenging effect of.three different blood purification of patients on maintenance hemodialysis parathyroid hormone(iPTH) and β2 microglobulin(β2-MG).【Methods】 90 patients with hemodialysis were randomly divided into three groups: The use of hemodialysis(HD) group of 30 patients,blood perfusion+hemodialysis(HP+HD) 30 cases,hemodiafiltration(HDF) group of 30 cases,treated groups were compared before and after a single treatment of blood iPTH and β2-MG clearance.【Results】 HP+HD group,HDF group,after treatment,serum iPTH and β2-MG were significantly decreased(P 0.05),HD group after treatment,serum iPTH and β2-MG was no significant decrease(P 0.05).【Conclusion】 Hemoperfusion+hemodialysis,hemodiafiltration and continuous hemodialysis filtration can effectively remove blood iPTH and β2-MG,long-term use can significantly improve the patient's quality of life and survival.

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【Objective】 To observe the scavenging effect of.three different blood purification of patients on maintenance hemodialysis parathyroid hormone(iPTH) and β2 microglobulin(β2-MG).【Methods】 90 patients with hemodialysis were randomly divided into three groups: The use of hemodialysis(HD) group of 30 patients,blood perfusion+hemodialysis(HP+HD) 30 cases,hemodiafiltration(HDF) group of 30 cases,treated groups were compared before and after a single treatment of blood iPTH and β2-MG clearance.【Results】 HP+HD group,HDF group,after treatment,serum iPTH and β2-MG were significantly decreased(P 0.05),HD group after treatment,serum iPTH and β2-MG was no significant decrease(P 0.05).【Conclusion】 Hemoperfusion+hemodialysis,hemodiafiltration and continuous hemodialysis filtration can effectively remove blood iPTH and β2-MG,long-term use can significantly improve the patient's quality of life and survival.

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Available abstract

【Objective】 To observe the scavenging effect of.three different blood purification of patients on maintenance hemodialysis parathyroid hormone(iPTH) and β2 microglobulin(β2-MG).【Methods】 90 patients with hemodialysis were randomly divided into three groups: The use of hemodialysis(HD) group of 30 patients,blood perfusion+hemodialysis(HP+HD) 30 cases,hemodiafiltration(HDF) group of 30 cases,treated groups were compared before and after a single treatment of blood iPTH and β2-MG clearance.【Results】 HP+HD group,HDF group,after treatment,serum iPTH and β2-MG were significantly decreased(P 0.05),HD group after treatment,serum iPTH and β2-MG was no significant decrease(P 0.05).【Conclusion】 Hemoperfusion+hemodialysis,hemodiafiltration and continuous hemodialysis filtration can effectively remove blood iPTH and β2-MG,long-term use can significantly improve the patient's quality of life and survival.

Key concepts: Hemodialysis, Medicine, Hemoperfusion, Beta-2 microglobulin, Parathyroid hormone, Urology, Internal medicine, Surgery

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