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Effect of different blood purification methods on parathyroid hormone in maintenance hemodialysis patients with secondary hyperparathyroidism

Weiming Sun

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Abstract

Objective To compare the effect of different blood purification methods on parathyroid hormone in maintenance hemodialysis patients with secondary hyperparathyroidism.Methods Fifty-three patients on maintenance hemodialysis were randomly divided into three groups: hemodialysis group(HD group),hemodiafiltration group(HDF group) and hemoperfusion plus hemodialysis group(HP+HD group).Serum phosphorus,calcium and serum PTH levels were observed before and after six month-continuing treatment.Results After being treated,the levels of serum PTH in HDF group and HP+HD group decreased significantly(all P0.01),so did the level of serum phosphorus in HP+HD group(P0.05).There were no changes of serum calcium in three groups.Conclusion Hemodiafiltration and hemoperfusion plus hemodialysis can effectively clear PTH in maintenance hemodialysis patients with secondary hyperparathyroidism.

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What this paper is about

Objective To compare the effect of different blood purification methods on parathyroid hormone in maintenance hemodialysis patients with secondary hyperparathyroidism.Methods Fifty-three patients on maintenance hemodialysis were randomly divided into three groups: hemodialysis group(HD group),hemodiafiltration group(HDF group) and hemoperfusion plus hemodialysis group(HP+HD group).Serum phosphorus,calcium and serum PTH levels were observed before and after six month-continuing treatment.Results After being treated,the levels of serum PTH in HDF group and HP+HD group decreased significantly(all P0.01),so did the level of serum phosphorus in HP+HD group(P0.05).There were no changes of serum calcium in three groups.Conclusion Hemodiafiltration and hemoperfusion plus hemodialysis can effectively clear PTH in maintenance hemodialysis patients with secondary hyperparathyroidism.

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Available abstract

Objective To compare the effect of different blood purification methods on parathyroid hormone in maintenance hemodialysis patients with secondary hyperparathyroidism.Methods Fifty-three patients on maintenance hemodialysis were randomly divided into three groups: hemodialysis group(HD group),hemodiafiltration group(HDF group) and hemoperfusion plus hemodialysis group(HP+HD group).Serum phosphorus,calcium and serum PTH levels were observed before and after six month-continuing treatment.Results After being treated,the levels of serum PTH in HDF group and HP+HD group decreased significantly(all P0.01),so did the level of serum phosphorus in HP+HD group(P0.05).There were no changes of serum calcium in three groups.Conclusion Hemodiafiltration and hemoperfusion plus hemodialysis can effectively clear PTH in maintenance hemodialysis patients with secondary hyperparathyroidism.

Key concepts: Hemoperfusion, Hemodialysis, Secondary hyperparathyroidism, Parathyroid hormone, Medicine, Hyperparathyroidism, Internal medicine, Urology

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Effect of different blood purification methods on parathyroid hormone in maintenance hemodialysis patients with secondary hyperparathyroidism — Research Paper | ScholarLens