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Effect of blood purification on plasma levels of intact parathyroid hormone in patients with chronic renal failure.

Jun Qi Liu, Zhiqiang Liu, Hui-qin Tao

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Abstract

OBJECTIVE: To study the effects of hemoperfusion and/or hemodialysis on plasma levels of intact parathyroid hormone (iPTH) in patients with chronic renal failure (CRF). METHODS: A total of 40 uremic patients were randomly divided into two groups to receive hemoperfusion in combination with hemodialysis (HP+HD) or exclusive hemodialysis (HD), respectively. Plasma iPTH concentration was measured by means of radio immunoassay. RESULTS: After the blood purification procedures, the patients' plasma iPTH levels were reduced from 1,508.70+/-1,268.89 to 1,049.04+/-992.91 microg/ml (P<0.001) in HD group and from 1,600.70+/-1,151.15 to 745.47+/-785.02 microg/ml (P<0.001) in HP+HD group. CONCLUSION: Blood purification with hemoperfusion plus hemodialysis may decrease plasma iPTH levels more efficiently than hemodialysis performed alone.

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What this paper is about

OBJECTIVE: To study the effects of hemoperfusion and/or hemodialysis on plasma levels of intact parathyroid hormone (iPTH) in patients with chronic renal failure (CRF). METHODS: A total of 40 uremic patients were randomly divided into two groups to receive hemoperfusion in combination with hemodialysis (HP+HD) or exclusive hemodialysis (HD), respectively. Plasma iPTH concentration was measured by means of radio immunoassay. RESULTS: After the blood purification procedures, the patients' plasma iPTH levels were reduced from 1,508.70+/-1,268.89 to 1,049.04+/-992.91 microg/ml (P<0.001) in HD group and from 1,600.70+/-1,151.15 to 745.47+/-785.02 microg/ml (P<0.001) in HP+HD group. CONCLUSION: Blood purification with hemoperfusion plus hemodialysis may decrease plasma iPTH levels more efficiently than hemodialysis performed alone.

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Available abstract

OBJECTIVE: To study the effects of hemoperfusion and/or hemodialysis on plasma levels of intact parathyroid hormone (iPTH) in patients with chronic renal failure (CRF). METHODS: A total of 40 uremic patients were randomly divided into two groups to receive hemoperfusion in combination with hemodialysis (HP+HD) or exclusive hemodialysis (HD), respectively. Plasma iPTH concentration was measured by means of radio immunoassay. RESULTS: After the blood purification procedures, the patients' plasma iPTH levels were reduced from 1,508.70+/-1,268.89 to 1,049.04+/-992.91 microg/ml (P<0.001) in HD group and from 1,600.70+/-1,151.15 to 745.47+/-785.02 microg/ml (P<0.001) in HP+HD group. CONCLUSION: Blood purification with hemoperfusion plus hemodialysis may decrease plasma iPTH levels more efficiently than hemodialysis performed alone.

Key concepts: Hemoperfusion, Hemodialysis, Parathyroid hormone, Medicine, Internal medicine, Chronic renal failure, Endocrinology, Urology

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Effect of blood purification on plasma levels of intact parathyroid hormone in patients with chronic renal failure. — Research Paper | ScholarLens