Influence of Early Enteral Nutrition on Postoperative Clinical Effects of Gastric Cancer Patients Treated with Radical Operations

Objective To investigate the influence of early enteral nutrition on gastric cancer patients after radical gastrectomy. Methods 100 cases of gastric cancer patients were randomly divided into the observation group and the control group, 50 cases in each group. The control group received parenteral nutrition therapy,the observation group were treated with early enteral nutrition therapy. The clinical outcomes of the 2 groups were observed and compared after treatment,,and postoperative immune function and nutritional status were evaluated. Results The time of postoperative fever,intestinal function recovery,exhaust,and hospitalization of the observation group were significantly shorter than those of the control group; CD3 +,CD4 +,CD4 + / CD8 +,NK and various immune cells activity of the 2 groups first day after surgery were significantly lower than before the surgery( P 0. 05),and CD8 + had no significant decrease,there was no significant difference( P 0. 05); the CD3 +,CD4 +, CD4 + / CD8 +,NK activity of various immune cells in the observation group after the first 7 days were( 35. 6 ± 4. 2) %,( 42. 2 ± 3. 0) %,( 1. 72 ± 0. 27) %,( 27. 3 ± 5. 3) %,respectively,close to the preoperative levels,while the control group was still significantly lower than before the surgery,and less than enteral nutrition group,P 0. 05,it was statistically significant. Conclusion Early enteral nutrition in patients treated with radical gastrectomy has better clinical outcome,immune function and nutritional status of patients are significantly improved,it is worth of clinical application.