Diagnosis and Prognosis Value of the Serum CA125、CA199、CEA Detection in Patients with Epithelinl Ovarian Cancer

Objective To probe into the clinical of detecting CA125、CA199 and CEA in diagnosis and prognosis of epithelial ovariancancer. Methods Serum levels of CA125、CA199 and CEA were measured by microparticle chemilum inescence method. Series of CA125、CA199 and CEA detem ination for patients with epithelial ovarian cancer in three months were carried out to observe the relationship of CA125、CA199、CEA value and therapeutic efficacy. Results The levels of CA125 and CA199 in Ovarian Cancer were significantly higher than those in benign ovarian tumor in ovarian cancer. The sensitivity of CA125、CA199、CEA were 72. 9% 、43. 8% 、22. 9% . The sensitivity of combined detection of three markers was 90. 0% . Conclusion The measurement of serum CA125 and CA199 in an effective method in the diagnosis and prognosis for patients with epithelial ovarian cancer. And the clinical value can be increased by the combined use of three marbers.