Clinical Observation of Citalopram Improve Depressive Symptoms in Parkinson's Disease Patients

Objective To observe citalopram on depressive symptoms in Parkinson's disease treatment.Methods In Shenzhen Longgang district people's hospital from January 2001 ～ December 2009 admitted 54 patients with Parkinson's disease with depression were randomly divided into two groups (citalopram in the treatment group) and control group (placebo group) of the 27 cases,course of treatment was 8 weeks,compared treatment effects.Results HAMD score before and after treatment control group,no significant difference (P0.05),while the effect of the therapy 2 weeks before treatment significantly different (P0.05),in the first 4 weeks,6 weeks,8 weeks and significantly different before treatment (P0.01);observation group total 5 cases of adverse reactions,accounting for 18.5%;control group a total of 4 cases of adverse reactions,accounting for 14.8%.Little difference between the two groups (P0.05).Conclusion Citalopram in improving depressive symptoms in Parkinson's disease results are satisfactory,and better safety.