2013•Medical Innovation of ChinaRequires access
The Relationship between Early Infection after Joint Arthroplasty and Peripheral Blood Lymphocytes
Liu Ri-guan
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Abstract
Objective:To explore the relationship between the early infection of surgical-site after artificial joint arthroplasty and peripheral blood lymphocytes. Method:A total of 30 joints of hip and knee replacement in the hospital from January 2001 to June 2012 had been analyzed retrospectively. To evaluate the surgical-site infection of artificial joint arthroplasty and the changes of peripheral blood lymphocytes on preoperative and the first, third postoperative day. The percentage of peripheral blood lymphocytes in patients with infection of different time was compared each other and to the control group(the number of peripheral blood lymphocytes in patients without infection after surgery)in statistical methods. To understand the changes in peripheral blood lymphocytes of such patients. Result:The percentage of peripheral blood lymphocytes in infected patients after the first,third postoperative day decreased significantly compared with the preoperative( P 0.05),and the changes in peripheral blood lymphocytes in the first、third postoperative day had no statistically significance(q test in the same cell). The percentage of peripheral blood lymphocytes in control group decreased significantly compared with the preoperative group on the first postoperative day( P 0.05),but the third postoperative day,the percentage of peripheral blood lymphocytes had no significant changes compared with the preoperative(q test in the same cell). The number of peripheral blood lymphocytes of infected group on the first. third postoperative day was significantly lower than that of the control group( P 0.05),and the lymphocyte recovery in infected group was slower than that of the control group. Conclusion:The peripheral blood lymphocytes decreased and recovered slowly in infected patients after joint arthroplasty. The detection of peripheral blood lymphocytes can reflect the immune status,which can guide us in control and prevent early infection after joint replacement.