The Short-term Prognosis Value of Plasam Copeptin and Hs-CRP Level in Patients with Acute Coronary Syndrome

Objective Through the determination of plasma copeptin,high sensitive C reactive protein(Hs-CRP) level,its effects on acute coronary syndrome(ACS) in patients with early diagnosis value.Methods Because chest pain was admitted to hospital with suspected ACS patients with 150 cases,according to coronary angiography(CAG) examination results were divided into normal group(control group,n=24),ACS group(n=126);according to coronary artery disease is divided into single vessel disease group(n=43),double vessel disease group(n=51),three-vessel group(n=22),left main disease group(n=10).Using the ELISA method for the determination of the incidence of 0～3h,3～6h,6～12h plasma copeptin level,the rate of light scattering turbidimetry determined at admission Hs-CRP level.Results Compared with control subjects,level of plasma Copeptin and Hs-CRP were higher in patients with ACS(P0.05).Especially the 0~3h plasma level of Copeptin were more higher.There were statistical difference among the three subgroups.In left main coronary stenosis group the level of plasma Copeptin is most high than orther groups(P0.05).The level of Hs-CRP is higher than other groups.There was no statistical difference(P0.05).Conclusion The plasma level of Copeptin is associated with short-term prognosis and may reflect the severity of impaired coronary arteries in patients with ACS.