2002•PubMedRequires access
[Studies of cytogenetic toxic effect of As2O3 on Vicia Faba root tip cells in vivo].
Xiao-Wei Qian, Xiaochun Zhu, Zhe-Xiao Chen, Liu-Qin Lin
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Abstract
The cytogenetic toxic effects of different concentration of As2O3 within different time on the cell of Vicia Faba root tip were studied. The results indicate that the different concentrations of As2O3 can induce high frequency of micronucleus and chromosome aberration. Besides, it can accumulate the metaphases in mitosis efficiently and prevent the cells from continuing their cell cycle. It shows that As2O3 has marked cytogenetic toxic effect on the root tip cells of Vicia Faba, and effect of accumulating the metaphases in mitosis.